Faculty |
Department |
Research Description |
Batista, Victor | Chemistry | QM/MM computational modeling of structure-function relations in macrobiomolecules |
Breaker, Ronald | MCDB |
Nucleic acids biochemistry and engineering, riboswitch and noncoding RNA discovery and analysis |
Brudvig, Gary | Chemistry (MB&B) |
Photosynthetic water oxidation; EPR spectroscopy; metalloproteins; biological electron-transfer reactions |
Cabral, João | MB&B | Structure/function of membrane proteins involved in ion permeation |
Crews, Craig | MCDB (Chemistry, Pharmacology) |
Natural product syntheses and mechanisms of actin studies |
De La Cruz, Enrique | MB&B | Mechanisms of energy transduction and allostery in molecular motors. Cooperative actin filament interactions |
Engelman, Donald | MB&B | Folding and oligomerization of membrane proteins: structural motifs, association energies, design principles |
Gerstein, Mark | MB&B (Computer Science) |
Bioinformatics: Large-scale analysis of genome sequences, macromolecular structures and expression data |
Jorgensen, William | Chemistry | Theoretical chemistry and biochemistry, computer aided drug design, and synthetic organic chemistry |
Loria, Patrick | Chemistry | Protein dynamics, enzyme function, NMR methods development |
Miranker, Andrew | MB&B | Protein folding, misfolding and assembly of pathogenic complexes |
Modis, Yorgo | MB&B | The structural basis of innate immune sensing and viral membrane fusion |
Moore, Peter | Chemistry (MB&B) |
Structure and function of ribosomes |
Pyle, Anna Marie | MB&B | RNA tertiary structure and folding of group II intron ribozymes; Translocation and unwinding mechanims of RNA helicase enzymes; Computational analysis of RNA structure |
Pollard, Thomas | MCDB (MB&B) |
Molecular mechanism of actin-based cellular motility and of cytokinesis |
Regan, Lynne | MB&B (Chemistry) |
Protein structure, function and design; protein-protein and protein-RNA interactions |
Rhoades, Elizabeth | MB&B | Characterization of protein conformation/dynamics; protein-protein interactions, and protein-membrane ineractions |
Schepartz, Alanna | Chemistry (MCDB) |
Developing chemical tools to study protein-protein and protein-DNA interactions inside the cell |
Snyder, Michael | MCDB (MB&B) |
Regulatory Networks: Large-scale analysis of eukaryotic genomes and proteomes |
Söll, Dieter | MB&B (Chemistry) |
Genomics of the translation apparatus |
Steitz, Thomas | MB&B |
X-ray diffraction and molecular biological structure/function studies of proteins and nucleic acids involved in replication, recombination, transcription and translation |
Strobel, Scott | MB&B | Structure and function of RNA: understanding the catalytic mechanism and tertiary structure of RNA enzymes |
Tully, John | Chemistry (Applied Physics, Physics) |
Theory of dynamics of chemical reactions at solid surfaces, in the condensed phase and in biological molecules |
Unger, Vinzenz | MB&B | Structure and function of integral membrane proteins and membrane associated scaffolds |
Valentine, Ann | Chemistry | Bioinorganic chemistry, particularly uptake, transport, and use of hydrolysis-prone elements and biomineralization |
Xiong, Yong |
MB&B | Structures and functions of host factors that restrict viral infection |
Chemistry | Molecular functions of G protein-coupled receptors | |
Zilm, Kurt |
Chemistry (Chemical Engineering) |
Development of solid state NMR methods to determine macromolecular stuctures and to study the physical chemistry of proteins in the solid state with a current emphasis on water dynamics and the protein glass transition |
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