Yan Lab

Liu, J.; Liu, M.; Mooney, V.; Bhagat, A.; Nguyen, J. & Yan, E.C.Y "Effect of Hydrogen-Bonds at the Retinal Binding Pocket: Thermal Isomerization of Rhodopsin versus Catalytic Isomerization of Opsin Protein" In Preparation, 2009.

Fu, L.; Ma, G.; Yan, E.C.Y. “In Situ Protein Folding at Interfaces by Sum Frequency Generation” Submitted, 2009

Ahuja, S.; Eilers, M.; Hirshfeld, A.; Yan, E.C.Y.; Ziliox, M.; Sakmar, T.P.; Sheves, M.; Smith, S.O. “6-s-cis Conformation and Polar Binding Pocket of the Retinal Chromophore in the Photoactivated State of Rhodopsin” Accepted, J. Am. Chem. Soc., 2009

Liu, J.; Liu, M.; Bhagat, A.; Nguyen,J.; Mooney, V. and & Yan, E.C.Y " Thermal Decay of Rhodopsin Involves both Thermal Isomerization of 11-cis Retinal in the Retinal Binding Site and Hydrolysis of Schiff Base." J. Am. Chem. Soc. 131, 8750, 2009. Online Copy

Ma, G; Liu, J.; Fu, L. & Yan, E.C.Y. "Probing Water and Biomolecules at the Air/Water Interface with a Broad-Bandwidth Vibrational Sum Frequency Generation Spectrometer from 3800 to 900 cm-1". Appl. Spectro. 63, 528. 2009. Online Copy

Ahuja,S.; Hornak,V.; Yan, E.C.Y.; Syrett, N.; Goncalves, J.; Hirshfeld, A.; Ziliox, M.; Sakmar, T.P.; Sheves, M.; Reeves, P.J.; Smith, S.O & Eilers, M. "Helix Movement is Coupled to Displacement of Extracellular Loop 2 in Rhodopsin Activation." Nat. Struct. Mol. Biol.16, 168. 2009. Online Copy

Ye, S.; Köhrer, C.; Huber, T.; Kazmi, M.; Yan, E.C.Y.; Sachdev, P.; Bhagat, A.; RajBhandary, U.L.; Sakmar, T.P. “Site-specific Incorporation of Keto Amino Acids Into Functional G Protein-Coupled Receptors Using Unnatural Amino Acid Mutagenesis” J. Biol. Chem. 283, 1525, 2008. Online Copy.

Yan, E.C.Y.; Lewis, J.W.; Szundi, I; Epps, J.; Bhagat, A.; Kliger, D.S. “Photointermediates of the Rhodopsin S186A Mutant as a Probe of the Hydrogen Bond Network in the Chromophore Pocket and Counterion Switch” Invited Paper, In Press, J. Phy. Chem. C., 2007. Online Copy.

Vogel, R.; Siebert, F; Yan, E.C.Y.; Sakmar, T.P.; Hirshfeld, A.; Sheves, M. “Modulating Rhodopsin Receptor Activation by Altering the pKa of the Retinal Schiff Base” J. Am. Chem. Soc. 128, 10503, 2006. Online Copy.

Ludeke, S; Beck, M.; Yan, E.C.Y.; Sakmar, T.P.; Siebert, F.; Vogel, R. “The Role of Glu181 in the Photoactivation of Rhodopsin.” J. Mol. Biol. 353, 245, 2005. Online Copy.

Yan, E.C.Y.; Gamin, Z.; Kazmi, M.A.; Chang, B.S.W.; Sakmar, T. P.; Mathies, R. A. “Resonance Raman Analysis of the Mechanism of Energy Storage and Chromophore Distortion in the Primary Visual Photoproduct” Biochemistry 43, 10867, 2004. Online Copy.

Yan, E.C.Y.; Kazmi, M.A.; Gamin, Z.; Hou, J. M.; Pan, D.; Chang, B.S.W.; Sakmar, T. P.; Mathies, R. A “Retinal counterion Switch in the Photoactivation of G Protein-Coupled Receptor Rhodopsin” Proc. Natl. Acad. Sci. U.S.A. 100, 9262, 2003. Online Copy.

Commentary by Birge, R.B. and Knox, B.E. “Perspectives on the counterion switch-induced photoactivation of the G protein-coupled receptor rhodopsin” Proc. Natl. Acad. Sci. U.S.A. 100, 9105, 2003. Online Copy.

Yan, E.C.Y.; Kazmi, M.A.; De, S; Chang, S.W.; Seibert, C.; Marin, E.P.; Mathies, R.A.; Sakmar, T.P. “Function of Extracellular Loop 2 in Bovine Rhodopsin: Glutamic Acid 181 Modulates Stability and Wavelength Maximal Absorption of Metarhodopsin II” Biochemistry 41, 3620, 2002. Online Copy.

Shang, X.; Liu, Y.; Yan, E.; Eisenthal, K.B. “Effect of Counterions on Molecular Transport across Liposome Bilayer: Probed by Second Harmonic Generation” J. Phys. Chem. B. 105, 12816, 2001. Online Copy.

Yan, E.C.Y.; Liu, Y.; Eisenthal, K.B. “In-situ Studies of Molecular Transfer between Colloidal Surfaces by Second Harmonic Generation” J. Phys. Chem. B. 105, 8531, 2001. Online Copy.

Liu, Y.; Yan, E.C.Y.; Zhou, X. L.; Eisenthal, K.B. “Surface Potential of Charged Liposomes Determined by Second Harmonic Generation” Langmuir 17, 2063, 2001. Online Copy.

Liu, Y.; Yan, E.C.Y.; Eisenthal, K.B. “Effect of Lipid Composition on Molecular Adsorption and Transport across Liposome Bilayers” Biophys. J. 80, 1004, 2001. Online Copy.

Yan, E.C.Y.; Eisenthal, K.B. “Effects of Cholesterol on Molecular Transport of Organic Cations across Liposome Bilayers Probed by Second Harmonic Generation” Biophys. J. 79, 898, 2000. Online Copy.

Yan, E.C.Y.; Eisenthal, K.B. “Rotational Dynamics of Anisotropic Particles Studied by Second Harmonic Generation” J. Phys. Chem. B. 104, 6686, 2000. Online Copy.

Yan, E.C.Y.; Eisenthal, K.B. “Probing the Interface of Microscopic Clay Particles in Aqueous Solution by Second Harmonic Generation” J. Phys. Chem. B. 103, 6056, 1999. Online Copy.

Yan, E.C.Y.; Liu, Y.; Eisenthal, K.B. “New Method for Determination of Surface Potential of Microscopic Particles by Second Harmonic Generation” J. Phys. Chem. B 102, 6331, 1998. Online Copy.

Wang, H.; Yan, E.C.Y.; Liu, Y.; Eisenthal, K.B. “Energetics and Population of Molecules at Microscopic Liquid and Solid Surfaces” J. Phys. Chem. 102, 4446, 1998.Online Copy.

Wang, H.; Borguet, E.; Yan, E.C.Y.; Zhang, D.; Gutow, J.; Eisenthal, K.B. “Molecules at Liquid and Solid Surfaces” Langmuir 14, 1472, 1998. Online Copy.

Wang, H.; Yan, E.C.Y.; Borguet, E.; Eisenthal, K.B. “Second Harmonic Generation from the Surface of Centrosymmetric Particles in Bulk Solution” Chem. Phys. Letts. 259, 15, 1996. Online Copy.

Wu, C.; Yan, C.Y. “Studies of the Swelling and Drying Kinetics of Thin Gel Films by In-Situ Interferometry” Macromolecules 27, 4516, 1994. Online Copy.

	Publications

	Liu, J.; Liu, M.; Mooney, V.; Bhagat, A.; Nguyen, J. & Yan, E.C.Y "Effect of Hydrogen-Bonds at the Retinal Binding Pocket: Thermal Isomerization of Rhodopsin versus Catalytic Isomerization of Opsin Protein" In Preparation, 2009. Fu, L.; Ma, G.; Yan, E.C.Y. “In Situ Protein Folding at Interfaces by Sum Frequency Generation” Submitted, 2009 Ahuja, S.; Eilers, M.; Hirshfeld, A.; Yan, E.C.Y.; Ziliox, M.; Sakmar, T.P.; Sheves, M.; Smith, S.O. “6-s-cis Conformation and Polar Binding Pocket of the Retinal Chromophore in the Photoactivated State of Rhodopsin” Accepted, J. Am. Chem. Soc., 2009 Liu, J.; Liu, M.; Bhagat, A.; Nguyen,J.; Mooney, V. and & Yan, E.C.Y " Thermal Decay of Rhodopsin Involves both Thermal Isomerization of 11-cis Retinal in the Retinal Binding Site and Hydrolysis of Schiff Base." J. Am. Chem. Soc. 131, 8750, 2009. Online Copy Ma, G; Liu, J.; Fu, L. & Yan, E.C.Y. "Probing Water and Biomolecules at the Air/Water Interface with a Broad-Bandwidth Vibrational Sum Frequency Generation Spectrometer from 3800 to 900 cm-1". Appl. Spectro. 63, 528. 2009. Online Copy Ahuja,S.; Hornak,V.; Yan, E.C.Y.; Syrett, N.; Goncalves, J.; Hirshfeld, A.; Ziliox, M.; Sakmar, T.P.; Sheves, M.; Reeves, P.J.; Smith, S.O & Eilers, M. "Helix Movement is Coupled to Displacement of Extracellular Loop 2 in Rhodopsin Activation." Nat. Struct. Mol. Biol.16, 168. 2009. Online Copy Ye, S.; Köhrer, C.; Huber, T.; Kazmi, M.; Yan, E.C.Y.; Sachdev, P.; Bhagat, A.; RajBhandary, U.L.; Sakmar, T.P. “Site-specific Incorporation of Keto Amino Acids Into Functional G Protein-Coupled Receptors Using Unnatural Amino Acid Mutagenesis” J. Biol. Chem. 283, 1525, 2008. Online Copy. Yan, E.C.Y.; Lewis, J.W.; Szundi, I; Epps, J.; Bhagat, A.; Kliger, D.S. “Photointermediates of the Rhodopsin S186A Mutant as a Probe of the Hydrogen Bond Network in the Chromophore Pocket and Counterion Switch” Invited Paper, In Press, J. Phy. Chem. C., 2007. Online Copy. Vogel, R.; Siebert, F; Yan, E.C.Y.; Sakmar, T.P.; Hirshfeld, A.; Sheves, M. “Modulating Rhodopsin Receptor Activation by Altering the pKa of the Retinal Schiff Base” J. Am. Chem. Soc. 128, 10503, 2006. Online Copy. Ludeke, S; Beck, M.; Yan, E.C.Y.; Sakmar, T.P.; Siebert, F.; Vogel, R. “The Role of Glu181 in the Photoactivation of Rhodopsin.” J. Mol. Biol. 353, 245, 2005. Online Copy. Yan, E.C.Y.; Gamin, Z.; Kazmi, M.A.; Chang, B.S.W.; Sakmar, T. P.; Mathies, R. A. “Resonance Raman Analysis of the Mechanism of Energy Storage and Chromophore Distortion in the Primary Visual Photoproduct” Biochemistry 43, 10867, 2004. Online Copy. Yan, E.C.Y.; Kazmi, M.A.; Gamin, Z.; Hou, J. M.; Pan, D.; Chang, B.S.W.; Sakmar, T. P.; Mathies, R. A “Retinal counterion Switch in the Photoactivation of G Protein-Coupled Receptor Rhodopsin” Proc. Natl. Acad. Sci. U.S.A. 100, 9262, 2003. Online Copy. Commentary by Birge, R.B. and Knox, B.E. “Perspectives on the counterion switch-induced photoactivation of the G protein-coupled receptor rhodopsin” Proc. Natl. Acad. Sci. U.S.A. 100, 9105, 2003. Online Copy. Yan, E.C.Y.; Kazmi, M.A.; De, S; Chang, S.W.; Seibert, C.; Marin, E.P.; Mathies, R.A.; Sakmar, T.P. “Function of Extracellular Loop 2 in Bovine Rhodopsin: Glutamic Acid 181 Modulates Stability and Wavelength Maximal Absorption of Metarhodopsin II” Biochemistry 41, 3620, 2002. Online Copy. Shang, X.; Liu, Y.; Yan, E.; Eisenthal, K.B. “Effect of Counterions on Molecular Transport across Liposome Bilayer: Probed by Second Harmonic Generation” J. Phys. Chem. B. 105, 12816, 2001. Online Copy. Yan, E.C.Y.; Liu, Y.; Eisenthal, K.B. “In-situ Studies of Molecular Transfer between Colloidal Surfaces by Second Harmonic Generation” J. Phys. Chem. B. 105, 8531, 2001. Online Copy. Liu, Y.; Yan, E.C.Y.; Zhou, X. L.; Eisenthal, K.B. “Surface Potential of Charged Liposomes Determined by Second Harmonic Generation” Langmuir 17, 2063, 2001. Online Copy. Liu, Y.; Yan, E.C.Y.; Eisenthal, K.B. “Effect of Lipid Composition on Molecular Adsorption and Transport across Liposome Bilayers” Biophys. J. 80, 1004, 2001. Online Copy. Yan, E.C.Y.; Eisenthal, K.B. “Effects of Cholesterol on Molecular Transport of Organic Cations across Liposome Bilayers Probed by Second Harmonic Generation” Biophys. J. 79, 898, 2000. Online Copy. Yan, E.C.Y.; Eisenthal, K.B. “Rotational Dynamics of Anisotropic Particles Studied by Second Harmonic Generation” J. Phys. Chem. B. 104, 6686, 2000. Online Copy. Yan, E.C.Y.; Eisenthal, K.B. “Probing the Interface of Microscopic Clay Particles in Aqueous Solution by Second Harmonic Generation” J. Phys. Chem. B. 103, 6056, 1999. Online Copy. Yan, E.C.Y.; Liu, Y.; Eisenthal, K.B. “New Method for Determination of Surface Potential of Microscopic Particles by Second Harmonic Generation” J. Phys. Chem. B 102, 6331, 1998. Online Copy. Wang, H.; Yan, E.C.Y.; Liu, Y.; Eisenthal, K.B. “Energetics and Population of Molecules at Microscopic Liquid and Solid Surfaces” J. Phys. Chem. 102, 4446, 1998.Online Copy. Wang, H.; Borguet, E.; Yan, E.C.Y.; Zhang, D.; Gutow, J.; Eisenthal, K.B. “Molecules at Liquid and Solid Surfaces” Langmuir 14, 1472, 1998. Online Copy. Wang, H.; Yan, E.C.Y.; Borguet, E.; Eisenthal, K.B. “Second Harmonic Generation from the Surface of Centrosymmetric Particles in Bulk Solution” Chem. Phys. Letts. 259, 15, 1996. Online Copy. Wu, C.; Yan, C.Y. “Studies of the Swelling and Drying Kinetics of Thin Gel Films by In-Situ Interferometry” Macromolecules 27, 4516, 1994. Online Copy.

		Updated Sep 09